American Liver Tumor Study Group Modified Tumor-Node-Metastasis (TNM) Staging Classification & for Hepatocellular Carcinoma
	
Classification	Definition	
TX, NX, MX 	Not assessed	
TO, NO, MO	Not found	
T1	1 nodule <1.9 cm	
T2	One nodule 2.0-5.0 cm; two or three nodules, all <3.0 cm	
T3	One nodule >5.0 cm; two or three nodules, at least one >3.0 cm	
T4a	Four or more nodules, any size	
T4b 	T2, T3, or T4a plus gross intrahepatic portal or hepatic vein involvement as indicated by CT, MRI, or ultrasound	
N1 	Regional (portal hepatis) nodes, involved	
M1	Metastatic disease, including extrahepatic portal or hepatic vein involvement	
Stage 1	T1	
Stage II	T2	
Stage III 	T3	
Stage IVA1	T4a	
Stage IVA2	T4b	
Stage IVB	Any N1, any M1